House treats a Black presidential candidate, whom House is convinced has AIDS, but the Senator’s passion convinces him otherwise. Also, Vogler forces House to give a speech endorsing a new drug from Vogler’s company, but House has plans of his own.
A morbidly obese ten-year-old girl has a heart attack, and her mother insists that House and his team look past her weight to find the diagnosis. Meanwhile, Vogler pressures House to fire a member of his staff. Clinic Patients: Unidentified man with an infected pierced scrotum; overweight woman with a 30-pound tumor on her ovaries who refuses to have it removed, because she worries she will be unattractive.
A company boss is admitted with unexplained paralysis and scans of her muscles and bones can find no cause for the problem, but when House probes her psychiatric history, he finds clues that lead him to a solution. However, it will require a transplant - which the committee are unlikely to grant if he tells the truth. Meanwhile, a new chairman of the hospital board takes an instant dislike to the grumpy medic. Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase.